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 BOOK CHAPTER AND REVIEWS

1.             Thornbury, K.D., Hollywood, M.A. & McHale, N.G. (1992).  Nitric oxide mediates NANC relaxation of the smooth muscle sphincter of the urinary bladder. In Biology of nitric oxide, ed S. Moncada, M.A. Marletta, J.B. Hibbs Jr & E.A. Higgs, Portland Press,  pp 309-312.

ABSTRACTS/CONFERENCE PROCEEDINGS

1.     Hollywood, MA., Thornbury, K.D. & McHale, N.G. (1992). Augmentation of sheep lymphatic contractility by L-NG-nitro arginine methyl ester. Journal of Physiology,  446, 420P.

2.      Thornbury, K.D., Hollywood, MA. & McHale, N.G. (1992).  Role of nitric oxide in neurogenic relaxation of the outlet of the outlet sphincter of the urinary bladder in the sheep. Journal of Physiology,  446, 422P.

3.     McHale NG, Hollywood MA (1993) Influence of nerves on lymphatic contractility. 14th International Congress of Lymphology, SEP 20-26, 1993Lymphology 27: 15-24 Suppl. S 1994

4.      Hollywood, M.A., Thornbury, KD., Keenan, A.K., Gierschik, P. and McHale, N.G. (1995).  Inward and outward currents in bovine lymphatic smooth muscle. Irish Journal of Medical Science , 164, 311.

5.      Cotton, K.D., Hollywood, M.A., Thornbury, KD. and McHale, N.G. (1996) Blockade of outward currents in isolated smooth muscle cells of the sheep bladder.Irish Journal of Medical Science  165, 225.

6.      Cotton, K.D., Hollywood, M.A., McHale, N.G., Thornbury, K.D. (1995). Evans-blue enhances outward current in isolated smooth-muscle cells of the sheep bladder.Journal of Physiology  489P, 137P.

7.      Hollywood, M.A., Cotton, K.D, Thornbury, K.D., McHale, N.G. (1995). Modulation by Evans-blue of Ca2+-dependent K+ current in isolated smooth-muscle cells from the sheep bladder.Journal of Physiology  489P, 137P-138P.

8.     Cotton, K.D., Hollywood, M.A., McHale, N.G., Thornbury, K.D. (1996). Enhancement by reactive blue 2 of outward current in isolated smooth muscle cells of the sheep bladder. Irish Journal of Medical Science  165, 307.

9.     Hollywood, M.A., Cotton, K.D, Thornbury, K.D., McHale, N.G. (1996). Modulation by cibacron blue of Ca2+-dependent K+ current in isolated smooth muscle cells from the sheep bladder. Irish Journal of Medical Science 165, 307-308.

10.  Cotton, K.D., Hollywood, M.A., McHale, N.G., Thornbury, K.D. (1996). Membrane currents in isolated lymphatic smooth muscle cells of the sheep.Journal of Physiology, 495, 98P.Hollywood, M.A., Cotton, K.D.  Thornbury, K.D. & McHale, N.G. (1996). Fast sodium current in isolated lymphatic smooth muscle cells of the sheep. Journal of Physiology, 495, 98-99P.

11.  Hollywood, M.A., Cotton, K.D.  Thornbury, K.D. & McHale, N.G. (1997). Isolated sheep mesenteric lymphatic smooth muscle cells possess both T- and L-type calcium currents. Journal of Physiology 501, 109P.

12.  Convery, M.C., Hollywood, M.A., Cotton, K.D.  Thornbury, K.D. & McHale, N.G. (1997). Role of inward currents in pumping activty of isolated sheep lymphatics.  Journal of Physiology, 501, 110-111P.

13.  Cotton, K.D., Hollywood, M.A., McHale, N.G., Thornbury, K.D. (1997). Ca2+-activated chloride currents in smooth muscle cells isolated from sheep urethra. Journal of Physiology, 501, 111-112P.

14.  Sergeant, G., Cotton, K.D.,Thornbury, K.D,  McHale, N.G. & Hollywood, M.A. (1997). The inhibitory effect of 5-HT on isolated sheep lymphatic vessels is blocked by penitrem A. Journal of Physiology 501, 116P.

15.  Kilbride, J., Cotton, K.D., Hollywood, M.A., McHale, N.G. & Thornbury, K.D. (1997). Characterisation of outward currents in isolated smooth muscle cells from the rat stomach.  Irish Journal of Medical Science  (in press).

16.  Hollywood, M.A., Toland, H.M., Cotton, K.D., Thornbury, K.D. & McHale, N.G. (1997). Characterisation of a calcium-activated chloride current in isolated sheep lymphatic smooth muscle cells. Journal of Physiology  505, 97P.

17.  Hollywood, M.A., Cotton, K.D., Thornbury, K.D. & McHale, N.G. (1998). Contribution of a penitrem A-sensitive current to the action potential in smooth muscle cells isolated from the sheep urethra. Journal of Physiology  509P P28-P29.

18.  Sergeant, G.P., Hollywood, M.A., Cotton, K.D., Thornbury, K.D. & McHale, N.G. (1998). Modulation of Ca2+-activated Cl- currents in sheep urethral smooth muscle cells. J. Physiol. 513P 95P-96P

19.  Cotton, K.D., Toland, H.M., Hollywood, M.A., Thornbury, K.D. & McHale, N.G. (1998). Characterization of a hyperpolarisation-activated current in isolated sheep mesenteric lymphatic smooth muscle cells. J. Physiol. 513P 95P

20.  Hollywood, M.A., McHale, N.G. and Thornbury,  K.D.  (1999) Persistence of the transient calcium-activated potassium current after store depletion in isolated rabbit urethral myocytes. J. Physiol. 515P, 179-180P.

21.  Brain, R.E., Sergeant, G.P., Hollywood, M.A., McHale, N.G. and Thornbury, K.D. (1999). Noradrenaline evoked contractions in isolated rabbit urethra depend on both calcium influx and intracellular release.J. Physiol. 515P, 180P.

22.  Toland, H.M., McCloskey, K.D., Hollywood, M.A., Thornbury, K.D. and McHale, N.G. (1999). Effects of blockade of the pacemaking current in isolated sheep mesenteric lymphatics.  Ir. J. Med. Sci. 168, 150.

23.  Sergeant, G.P., Hollywood, M.A., McHale, N.G. and Thornbury, K.D. (1999) Carbachol-evoked chloride currents in isolated sheep urethral smooth muscle cells. Ir. J. Med. Sci. 168, 149.

24.  Hollywood MA, Sergeant GP, McCloskey KD, McHale NG, Thornbury KD Effects of the IP3-induced Ca2+ release modulator 2-aminoethoxydiphenylborate on calcium-activated currents in interstitial cells isolated the rabbit urethra. Journal of Physiology 528P: 2P-3P Sp. Iss. SI NOV 2000 ISSN:0022-375

25.  Sergeant GP, Hollywood MA, McCloskey KD, McHale NG, Thornbury KD. Role of IP3 in modulation of spontaneous activity in pacemaker cells of the rabbit urethra. Journal of Physiology 528P: 3P-3P Sp. Iss. SI NOV 2000, ISSN:0022-3751

26.  Carty M, Thornbury KD, McHale NG, Hollywood MA Effect of chloride channel blockers on spontaneous contractions in smooth muscle strips from the rabbit bladder. Journal of Physiology 528P: 8P-8P Sp. Iss. SI NOV 2000, ISSN:0022-3751

27.  Robinson D, Thornbury KD, Hollywood MA, McHale NG. Role of calcium-activated chloride current in spontaneous pumping of sheep lymphatic smooth muscle. Journal of Physiology 528P: 8P-9P Sp. Iss. SI NOV 2000, ISSN:0022-3751

28.  McCloskey KD, Hollywood MA, Thornbury KD, Ward SM, McHale C-kit-positive cells in lymphatic vessels. Journal of Physiology 528P: 11P-11P Sp. Iss. SI NOV 2000, ISSN:0022-3751

29.  Hollywood MA, Sergeant GP, McCloskey KD, McHale NG, Thornbury KD. Effects of the IP3-induced Ca2+ release modulator 2-aminoethoxydiphenylborate on calcium-activated currents in interstitial cells isolated from the rabbit urethra Journal of Physiology 528P: 2P-3P Sp. Iss. SI NOV 2000, ISSN:0022-3751.

30.  Hollywood MA, Sergeant GP, McCloskey KD, McHale, NG and Thornbury, KD.  Effects of the IP3-induced Ca2+ release modulator 2-aminoethoxydiphenylborate on calcium-activated currents in interstitial cells isolated from  the rabbit urethra. J PHYSIOL-LONDON 528P: 2P-3P Sp. Iss. SI NOV 2000, ISSN:0022-3751.

31.  Hollywood, MA, Thornbury KD,. Walsh IA, Keane PF and McHale NG Characterisation of low- and high-voltage-activated inward currents in smooth muscle cells of human bladder neck. Journal of Physiology. Pub: Cambridge Univ. Press, 2001, Vol. 536P, pp 90P, ISSN: 0022-3751.

32.  McKeag, NA, Thornbury KD, Hollywood, and McHale NGRole of calcium-activated chloride channels in myogenic tone in the rat urethra.Journal of Physiology. Pub: Cambridge Univ. Press, 2001, Vol. 536P, pp 93P, ISSN: 0022-3751.

33.  Beckett, EAH, Glasgow, N., Thornbury KD, Hollywood, MA and McHale NG Effect of noradrenaline on freshly dispersed interstitial cells from the rabbit urethra. Journal of Physiology. Pub: Cambridge Univ. Press, 2001, Vol. 536P, pp 96P, ISSN: 0022-3751

34.  Sergeant, GP, Thornbury KD, McHale NG and Hollywood, MA. Spontaneous and evoked action potentials in sheep mesenteric lymphatic vessels. Journal of Physiology. Pub: Cambridge Univ. Press, 2001, Vol. 536P, pp 95P, ISSN: 0022-3751

35.  Thornbury KD, Sergeant GP, McHale NG, and Hollywood, MA. IP3-induced calcium release activates calcium-activated chloride current following depolarization in interstitial cells isolated from the rabbit urethra.Biophys J 82 (1): 1377 Part 2 JAN 2002.

36.  Siobhan Woolsey, K.D. Thornbury, N.G. McHale and M.A. Hollywood (2002). Effects of noradrenaline on transient BK current in freshly dispersed smooth muscle cells from the rabbit urethra.  Journal of Physiology 543P  S154

37.  M.A. Hollywood, K.D. Thornbury, S. Woolsey, I. Walsh, P. Keane and N.G. McHale (2002).  T-type calcium currents in freshly dispersed smooth muscle cells isolated from human proximal urethra Journal of Physiology543P  S153

38.  M. Craven, M.A. Hollywood, N.G. McHale and K.D. Thornbury.  (2002). Chloride currents in myocytes from the corpus cavernosum.  International Journal of Impotence Research 14, Suppl 4, S6, P-003.

39.  J.E. Bradley, U.A. Anderson, S.M. Woolsey, N.G. McHale, K.D. Thornbury and M.A. Hollywood (2003).  Characterisation of T-type calcium current and its role in spontaneous activity in rabbit urethral smooth muscle. Journal of Physiology 548P  P70

40.  Ursula A. Anderson, M.A. Hollywood, K.D. Thornbury and N.G. McHale (2003) Intracellular recording of spontaneous electrical activity in the isolated rabbit urethra Journal of Physiology 548P  P69

41.  C. G. Coates, D. J. Denvir, Emer Conroy, N. G. McHale, K.D. Thornbury, M. A. Hollywood (2003) Back illuminated electron multiplying technology: the world’s most sensitive CCD for ultra low-light microscopy Proc. SPIE Int. Soc. Opt. Eng. 4962, 319-328.

42.  C. G. Coates, D. J. Denvir, N. G. McHale, K.D. Thornbury, M. A. Hollywood (2003). Ultrasensitivity, speed and resolution: Optimising low-light microscopy with the back-illuminated electron multiplying CCD. Proc. SPIE Int. Soc. Opt. Eng 5139, 56-66.

43.  Mark A. Hollywood, Keith D. Thornbury, Colin Coates, Donal Denvir and Noel G. McHale (2003). Detection of spontaneous calcium release at rapid frame rates by a novel back illuminated electron multiplying charge coupled device Journal of Physiology  552P  P60.

44.  M.A. Hollywood, L. Johnston, N.G. McHale and K.D. Thornbury (2003).  Spontaneous calcium transients in isolated interstitial cells from the rabbit urethra. Journal of Physiology 548P  O16

45.  M. Shafei, K.D. Thornbury, N.G. McHale and M.A. Hollywood (2003).  Relative contributions of calcium influx and calcium stores to myogenic tone in the rat urethra Journal of Physiology 548P  O15.

46.  M. Craven, M.A. Hollywood, N.G. McHale and K.D. Thornbury (2003)  Effects of L-nitrosocysteine and the soluble guanylate cyclase activator YC-1 on calcium-activated chloride currents in freshly dispersed cells from rabbit corpus cavernosum Journal of Physiology 552P  P57

47.  M. Craven, M.A. Hollywood, N.G. McHale and K.D. Thornbury (2003). Evidence for a calcium-activated chloride current in freshly dispersed cells from rabbit corpus cavernosum Journal of Physiology 548P  O17.

48.  Coates C, Denvir, D, Haron I, Hollywood M, Thornbury K, McHale, N(2004). EMCCD - The definitive ultra low-light solution? Biophysical Journal  Volume: 86(10) S151A-151A.

49.  C. McCloskey, M. A. Hollywood, G.P. Sergeant, N.G. McHale & K.D. Thornbury  (2005) Characterisation of low voltage activated and high voltage activated inward currents in rabbit corpus cavernosum smooth muscle cells. Irish J Med Sci;174(2) p 14

50.  A. De Faoite, G.P. Sergeant,N.G. McHale, K.D. Thornbury, & M.A. Hollywood (2005) Inhibition of electrical activity in the isolated rabbit urethra by NO donors and activators of the guanylate cyclase pathway. Irish J Med Sci;174(2) p 27

51.  E. Bradley, M.A. Hollywood, N.G McHale, K.D Thornbury and G.P. Sergeant. (2005) Pacemaker activity in urethral interstitial cells is not dependent on capacitative calcium entry. Irish J Med Sci;174(2) p 12

52.  Victoria Cagney, G. P. Sergeant, M.A. Hollywood, N. G. McHale & K.D. Thornbury. (2008). Mechanisms underlying spontaneous Ca2+ waves in smooth muscle cells isolated from the mouse corpus cavernosum. Oral Presentation to RAMI at DkIT, June 2008.  To be published in Irish Journal of Medical Science.

53.  Claire Doyle, G. P. Sergeant, S.A. Bourke, M.A. Hollywood, N. G. McHale & K.D. Thornbury (2008). Spontaneous electrical activity in rabbit corpus cavernosum interstitial cells of Cajal. Poster Presentation to RAMI at DkIT, June 2008.  To be published in Irish Journal of Medical Science.

54.  B. Kyle, E. Bradley, K.D. Thornbury, N.G. McHale, G.P. Sergeant, S.Ohya, M.A. Hollywood (2008). Contribution of Kv2 channels to the delayed rectifier in freshly dispersed rabbit urethral myocytes. Oral Presentation to RAMI at DkIT, June 2008.  To be published in Irish Journal of Medical Science.

55.  A. DeFaoite, K.D. Thornbury, N.G. McHale, G.P. Sergeant, & M.A. Hollywood (2008). Modulation of tone in the rabbit proximal urethra by muscarinic agonists. Oral Presentation to RAMI at DkIT, June 2008.  To be published in Irish Journal of Medical Science.

56.  C. Doyle, G. P. Sergeant, M.A. Hollywood, N.G. McHale & K.D. Thornbury. (2009) Effect of ATP on isolated corpus cavernosum smooth muscle cells. Irish Journal of Medical Science.

57.  R.J. Large, M.A. Hollywood, G.P. Sergeant, K.D. (2009) Thornbury, J.R. Levick & N.G. McHale (2009) KV1.1 subunits contribute to the delayed rectifier cuurent in cultured rabbit knee synoviocytes. To be published inIrish Journal of Medical Science.

58.  M.A. Hollywood, B. Kyle, E. Bradley, K.D.Thornbury, G.P. Sergeant, N.G. McHale (2009) The transient BK current in freshly dispersed rabbit urethra is dependent on Ca2+ influx and Ca2+ release from ryanodine sensitive stores. To be published in Irish Journal of Medical Science.

59.  G. P. Sergeant1, M. A. Hollywood1, K. D. Thornbury1, N. G. McHale1 (2009) Role of mitochondria in modulating calcium oscillations in Interstitial Cells of Cajal
 Proc Physiol Soc 15 SA79

60.  A. De Faoite1, K. D. Thornbury1, N. G. McHale1, G. P. Sergeant1, M. A. Hollywood1 Muscarinic stimulation enhances spontaneous electrical activity in the rabbit urethra through activation of M3 receptors.
 (2009) Proc Physiol Soc 15 PC37

61.  Kadima1, M. A. Hollywood1, K. D. Thornbury1, N. G. McHale1 . Excitatory effects of ATP on rabbit urethra smooth muscle
G. P. Sergeant1, S. Kadima1, M. A. Hollywood1, K. D. Thornbury1, N. G. McHale1 (2009) Proc Physiol Soc 15 PC218

62.  G. P. Sergeant1, V. Cagney1, M. A. Hollywood1, N. G. McHale1, K. D. Thornbury1  Role of Ca2+-activated Cl- channels and Ca2+ influx in generating spontaneous intracellular Ca2+ waves in myocytes isolated from rabbit corpus cavernosum
 (2009) Proc Physiol Soc 15 PC217

63.  G. P. Sergeant1, C. Doyle1, M. A. Hollywood1, N. G. McHale1, K. D. Thornbury1 Effect of ATP on interstitial cells of Cajal isolated from the rabbit corpus cavernosum
 (2009) Proc Physiol Soc 15 PC216

64.  R. A. Large1, M. A. Hollywood1, G. P. Sergeant1, K. D. Thornbury1, J. R. Levick2, N. McHale1  Electrophysiology of Rabbit Cultured Synoviocytes
 (2009) Proc Physiol Soc 15 C15

65.  G. P. Sergeant1, E. Bradley1, B. Drumm1, M. A. Hollywood1, N. G. McHale1, K. D. Thornbury1 Regulation of spontaneous activity in interstitial cells of Cajal of the rabbit urethra by ATP
 (2009) Proc Physiol Soc 15 C139

66.  B. Kyle1, E. P. Bradley1, K. D. Thornbury1, N. G. McHale1, G. P. Sergeant1, S. Ohya2, M. A. Hollywood1  Delayed rectifier currents in freshly dispersed rabbit urethral myocytes are encoded by KV2.1.
 (2009) Proc Physiol Soc 15 C13

67.  Claire Doyle, G. P. Sergeant, M.A. Hollywood, N. G. McHale & K.D. Thornbury.  Effect of ATP on isolated rabbit corpus cavernosum smooth muscle cells. Ir J Med Sci. 2009 Nov;178

68.  Drumm, B, Sergeant, G. P., Hollywood, M. A. Thornbury, K. D., Harvey, B. & McHale, N. G. (2010). Origin of calcium oscillations in interstitial cells of the rabbit urethra. Ir J Med Sci.Volume: 179   Supplement: 7   Pages: S291-S292

69.  Kadima, S.; Hollywood, M. A.; Thornbury, K. D.; McHale, N. G. Sergeant, G. P. (2010). Regulation of urethral tone by ATP. Ir J Med Sci. Volume: 179   Supplement: 7 Pages: S286   

70.  Large, R.; Sergeant, G. P.; Webb, T., N. G. McHale1, K. D. Thornbury, Hollywood, M.A. (2010). Biophysical and pharmacological characterisation of herg (kv11.1) currents stably expressed in human embryonic kidney cells for cardiac safety testing. Ir J Med Sci. Volume: 179   Supplement: 7   Pages: S298-S299.

71.  C. Doyle, G. P. Sergeant, M. A. Hollywood, N. G. McHale, K. D. Thornbury. (2011). Effect of modulators of the nitric oxide/cGMP pathway on L-type Ca2+ current in rabbit corpus cavernosum smooth muscle cells.  Proc Physiol Soc 23  PC360.

72.  E. Bradley, T. Webb, G. P. Sergeant, M. A. Hollywood, N. G. McHale, K. D. Thornbury. Properties of a Na+ current in freshly dispersed smooth muscle cells from the rabbit airway (2011). Proc Physiol Soc 23, PC351.

73.   B. J. Drumm, M. A. Hollywood, G. P. Sergeant, K. D. Thornbury, B. J. Harvey, N. G. McHale (2011).  Effect of high external potassium on spontaneous calcium oscillations in isolated ICC from the rabbit urethra. Proc Physiol Soc 23, PC350.

74.  S. Roy, A. Akande1, R. Large, T. Webb, G. P. Sergeant, N. G. McHale1, K. D. Thornbury, M. A. Hollywood (2012). Structure activity relationships of novel BK channel modulators: The GoSlo-SR familyProc Physiol Soc 27 PC351.

75.  B. Drumm, G. Sergeant, B. Harvey, M. Hollywood, N. McHale, K. Thornbury (2012). Role of Ca2+ influx and diffusion in the initiation and propagation of calcium waves in ICC freshly isolated from the rabbit urethra Proc Physiol Soc 27, PC353.

76.  R. Large, T. I. Webb, A. Akande1, S. Roy, G. P. Sergeant, K. D. Thornbury, N. G. McHale, M. A. Hollywood (2012) Functional Ca2+ sensors do not contribute to the effect of the novel BK channel agonist GoSlo-SR5-6. Proc Physiol Soc 27 PC169.